Dextroamphetamine

Category: stimulant

Aliases: Dexedrine, D-amphetamine

Pharmacological Mechanism

Releases dopamine + norepinephrine via TAAR1 activation and reversal of DAT/NET vesicular transporters. Pure d-isomer is more CNS-selective (vs racemic MAS); narrower peripheral sympathetic profile than l-amphetamine.

Half-Life (t½)

PO: 10h

Dosing Guidelines

Target Organ Systems