Category: hormone
Aliases: Decadron, 9α-fluoro-16α-methyl-prednisolone
9α-fluorinated, 16α-methylated synthetic GR agonist — long biologic half-life (~36–54 h), negligible mineralocorticoid activity. Pure anti-inflammatory / immunosuppressive profile without sodium retention. HPA-axis suppression at supraphysiologic doses is profound (a single 1 mg dose suppresses ACTH → cortisol for >24 h — the overnight dexamethasone suppression test).
PO: 4h, IV: 4h, IM: 4h