CoQ10

Category: terpenoid

Aliases: Ubiquinone, Ubiquinol (reduced form), Coenzyme Q10

Pharmacological Mechanism

Electron-transport-chain mobile carrier between Complex I/II and Complex III. Endogenously synthesised through the mevalonate pathway (the same pathway statins inhibit — rationale for CoQ10 in statin-induced myopathy). Also a lipid-phase antioxidant, regenerated from ubiquinone to ubiquinol by cellular redox enzymes.

Half-Life (t½)

PO: 33h

Dosing Guidelines

Target Organ Systems

Interactions