Clobetasol Propionate

Category: topical

Aliases: Temovate

Pharmacological Mechanism

Super-high-potency topical glucocorticoid (Class I — most potent) — fluorinated + chlorinated steroid. Reserved for severe psoriasis, lichen planus, recalcitrant dermatitis. Two-week max courses on limited body areas to avoid HPA axis suppression and skin atrophy.

Half-Life (t½)

TD: 6h

Dosing Guidelines

Target Organ Systems