Clindamycin (topical)

Category: topical

Pharmacological Mechanism

Topical 1% clindamycin gel/solution/foam for acne. Same 50S ribosomal blockade as oral. Less resistance development than topical erythromycin; standard combination with benzoyl peroxide (Duac, Acanya).

Half-Life (t½)

TD: 12h

Dosing Guidelines

• TD: Typical 20mg (Range: 10 - 30 mg)

Target Organ Systems

• integumentary