Chlorpheniramine

Category: pharmacological

Aliases: Chlor-Trimeton

Pharmacological Mechanism

First-generation H1 antagonist — common OTC component of multi-ingredient cold/allergy products. Sedating + anticholinergic burden. Less drowsy at low dose than diphenhydramine.

Half-Life (t½)

PO: 27h

Dosing Guidelines

• PO: Typical 4mg (Range: 4 - 24 mg)

Target Organ Systems

• nervous
• immune-hematologic