Chlorogenic Acid

Category: polyphenol

Aliases: CGA, 5-O-caffeoylquinic acid

Pharmacological Mechanism

Caffeoylquinic ester — most abundant polyphenol in coffee + green coffee bean extract. Inhibits hepatic glucose-6-phosphatase → modest fasting glucose lowering. Antioxidant; the metabolite caffeic acid contributes to cardiovascular benefit.

Half-Life (t½)

PO: 2h

Dosing Guidelines

Target Organ Systems