Chlorhexidine

Category: topical

Aliases: Peridex, Hibiclens

Pharmacological Mechanism

Cationic biguanide antiseptic — disrupts bacterial cell membranes; strongly binds oral mucosa and dental pellicle giving ≥12h sustained activity. Oral rinse for periodontitis + post-surgical dental hygiene; surgical scrub formulation. Mild reversible tooth staining at chronic use.

Half-Life (t½)

TD: 12h

Dosing Guidelines

Target Organ Systems