Category: peptide
Aliases: Cetrotide, SB-75
Decapeptide GnRH antagonist (D-Nal⁶ substitution and acetylated N-terminus) developed from ovine GnRH-antagonist templates. In controlled ovarian stimulation, direct GnRH-R blockade prevents the premature LH surge without the 2-week agonist down-regulation protocol — enabling shorter IVF cycles. Single 3 mg dose covers ~4 days; multiple 0.25 mg daily doses dial the antagonism more precisely.
SC: 63h