Cetirizine

Category: pharmacological

Aliases: Zyrtec

Pharmacological Mechanism

Second-generation H1 antagonist — carboxylic acid form of hydroxyzine; reduced BBB penetration but slightly more sedating than loratadine / fexofenadine. Renally cleared.

Half-Life (t½)

PO: 7.4h

Dosing Guidelines

• PO: Typical 10mg (Range: 5 - 10 mg)

Target Organ Systems

• nervous