Cefuroxime

Category: pharmacological

Aliases: Ceftin, Zinacef

Pharmacological Mechanism

Second-generation cephalosporin β-lactam — better gram-negative + β-lactamase stability than first-generation. Oral axetil prodrug + IV form. Common for acute otitis media + bronchitis + Lyme disease (early).

Half-Life (t½)

PO: 1.5h, IV: 1.5h

Dosing Guidelines

• PO: Typical 500mg (Range: 250 - 500 mg)

Target Organ Systems

• respiratory
• immune-hematologic