CBG

Category: alkaloid

Aliases: Cannabigerol

Pharmacological Mechanism

"Mother" phytocannabinoid — biosynthetic precursor to THC, CBD, CBC. Weak CB1/CB2 modulator; α2-adrenergic agonist; 5-HT1A antagonist. Limited clinical data; growing supplement-market interest.

Half-Life (t½)

PO: 24h

Dosing Guidelines

• PO: Typical 50 mg (Range: 10–150 mg)

Target Organ Systems

• nervous

Pathways It Modulates

• Endocannabinoid system (activator) — CB1/CB2 weak + α2-adrenergic + 5-HT1A

Chemical Identifiers

• PubChem CID: 5315659
• Formula: C21H32O2
• Molecular weight: 316.48 g/mol
• InChIKey: QXACEHWTBCFNSA-SFQUDFHCSA-N
• SMILES: CCCCCC1=CC(=C(C(=C1)O)C/C=C(\C)/CCC=C(C)C)O

References

• PMID 20002104