Captopril

Category: pharmacological

Aliases: Capoten

Pharmacological Mechanism

First-developed ACE inhibitor — short-acting, sulfhydryl-containing. Faster onset than enalapril (active drug, no prodrug) supports use in hypertensive urgency. Sulfhydryl group may contribute to higher rash + dysgeusia (metallic taste) than newer ACEi.

Half-Life (t½)

PO: 2h

Dosing Guidelines

Target Organ Systems