Butenafine

Category: topical

Aliases: Lotrimin Ultra, Mentax

Pharmacological Mechanism

Benzylamine antifungal — squalene epoxidase inhibitor (same enzyme as terbinafine). Topical for tinea pedis, cruris, corporis. OTC strength of 1% cream.

Half-Life (t½)

TD: 24h

Dosing Guidelines

• TD: Typical 10 mg (Range: 10–30 mg)

Target Organ Systems

• integumentary
• immune-hematologic

Chemical Identifiers

• PubChem CID: 2484
• Formula: C23H27N
• Molecular weight: 317.47 g/mol
• InChIKey: ABJKWBDEJIDSJZ-UHFFFAOYSA-N
• SMILES: CC(C)(C)C1=CC=C(C=C1)CN(C)CC2=CC=CC3=CC=CC=C32