Bufotenin

Category: alkaloid

Aliases: bufotenine, 5-HO-DMT, 5-hydroxy-DMT, mappine

Pharmacological Mechanism

5-hydroxy-DMT, a tryptamine found in Bufo toad venom and Anadenanthera seeds; a 5-HT2A / 5-HT1A agonist. Central psychoactivity is debated (poor blood-brain-barrier penetration as the free base), while peripheral cardiovascular and autonomic effects are prominent.

Dosing Guidelines

Target Organ Systems