Bromantane

Category: nootropic

Aliases: Ladasten, Bromantan

Pharmacological Mechanism

Adamantane scaffold (related to amantadine). Weak DAT inhibition + tyrosine hydroxylase induction → subtle catecholaminergic boost. Non-classical stimulant profile — 'actoprotector' category in Russian pharmacology. Originally developed for Soviet military anti-fatigue applications.

Half-Life (t½)

PO: 10h

Dosing Guidelines

• PO: Typical 66.7 mg (Range: 50–100 mg)

Target Organ Systems

• nervous

Pathways It Modulates

• AMPA + kainate glutamate receptor modulation (activator) — dopaminergic + serotonergic (adamantane derivative)

Chemical Identifiers

• PubChem CID: 4660557
• Formula: C16H20BrN
• Molecular weight: 227.34 g/mol
• InChIKey: LWJALJDRFBXHKX-UHFFFAOYSA-N
• SMILES: C1C2CC3CC1CC(C2)C3NC4=CC=C(C=C4)Br

References

• PMID 7795204