Brimonidine

Category: pharmacological

Aliases: Alphagan

Pharmacological Mechanism

Selective α2-adrenergic agonist (ophthalmic) — reduces aqueous humor production + increases uveoscleral outflow. Used in open-angle glaucoma + ocular hypertension. Topical rosacea formulation (Mirvaso) uses the same compound for vasoconstrictive erythema reduction.

Half-Life (t½)

TD: 3h

Dosing Guidelines

• TD: Typical 0.2mg (Range: 0.1 - 0.2 mg)

Target Organ Systems

• cardiovascular
• integumentary