Bismuth Subsalicylate

Category: pharmacological

Aliases: Pepto-Bismol

Pharmacological Mechanism

OTC GI agent — anti-secretory + anti-inflammatory + mild antimicrobial via bismuth + salicylate moieties. Used for traveler's diarrhea, acute gastroenteritis, H. pylori eradication regimens. Black tongue / stool from bismuth sulfide; salicylate burden contraindicates with anticoagulants.

Half-Life (t½)

PO: 5h

Dosing Guidelines

• PO: Typical 525mg (Range: 525 - 4200 mg)

Target Organ Systems

• digestive
• immune-hematologic