α-Bisabolol

Category: terpenoid

Aliases: Levomenol

Pharmacological Mechanism

Sesquiterpene alcohol — primary anti-inflammatory active in chamomile + candeia tree. Inhibits NF-κB + reduces inflammatory cytokine release in keratinocytes. Common cosmetic ingredient at 0.1–1% for soothing irritated / sensitive skin.

Half-Life (t½)

TD: 8h

Dosing Guidelines

• TD: Typical 5 mg (Range: 1–10 mg)

Target Organ Systems

• integumentary
• immune-hematologic

Pathways It Modulates

• Nrf2 / Keap1 antioxidant response (activator) — anti-inflammatory + antimicrobial

Chemical Identifiers

• PubChem CID: 10586
• Formula: C15H26O
• Molecular weight: 222.37 g/mol
• InChIKey: RGZSQWQPBWRIAQ-UHFFFAOYSA-N
• SMILES: CC1=CCC(CC1)C(C)(CCC=C(C)C)O