Bictegravir

Category: pharmacological

Pharmacological Mechanism

Second-generation HIV INSTI — higher barrier to resistance than dolutegravir. Co-formulated with TAF + emtricitabine as Biktarvy, a single-tablet once-daily HIV regimen.

Half-Life (t½)

PO: 17.3h

Dosing Guidelines

• PO: Typical 50mg (Range: 50 - 50 mg)

Target Organ Systems

• immune-hematologic