Bicalutamide

Category: pharmacological

Aliases: Casodex

Pharmacological Mechanism

First-generation non-steroidal AR antagonist. Used in combined androgen blockade for prostate cancer; also off-label for transgender hormone therapy as an antiandrogen with minimal endocrine side effects. CYP3A4 substrate.

Half-Life (t½)

PO: 144h

Dosing Guidelines

Target Organ Systems