Betamethasone

Category: pharmacological

Aliases: Diprolene

Pharmacological Mechanism

High-potency fluorinated synthetic glucocorticoid (~25× cortisol). Topical Class I-III strength depending on vehicle + ester form. Systemic IM/IV used for fetal lung maturation in preterm labor. Cushingoid risk with chronic high-potency topical use over large body areas.

Half-Life (t½)

TD: 5h, PO: 8.1h, IV: 8.1h, IM: 8.1h

Dosing Guidelines

Target Organ Systems