β-Sitosterol

Category: lipid

Aliases: Beta-sitosterol, 24-ethylcholesterol

Pharmacological Mechanism

The most abundant dietary phytosterol (plant analogue of cholesterol). Competes with cholesterol for incorporation into mixed micelles and inhibits NPC1L1-mediated intestinal cholesterol absorption, lowering LDL — the basis of plant-sterol-enriched functional foods (~2 g/day).

Dosing Guidelines