Category: pharmacological
Aliases: Lioresal
GABA-B receptor agonist — pre- and post-synaptic K+ conductance activation reduces spinal cord motor neuron excitability. First-line for spasticity in MS, spinal cord injury, cerebral palsy. Intrathecal pump for severe cases. Withdrawal seizures + rebound spasticity if abruptly stopped.
PO: 4h