Aniracetam

Category: nootropic

Aliases: Draganon, Sarpul

Pharmacological Mechanism

Racetam with anxiolytic / anti-anhedonia component + AMPA positive modulation. Fat-soluble — better CNS penetration than piracetam. Extensively metabolised to N-anisoyl-GABA + anisic acid on first pass.

Half-Life (t½)

PO: 2h

Dosing Guidelines

• PO: Typical 1000 mg (Range: 750–1500 mg)

Target Organ Systems

• nervous
• digestive

Pathways It Modulates

• AMPA + kainate glutamate receptor modulation (activator) — AMPA (allosteric positive)

Chemical Identifiers

• PubChem CID: 2196
• Formula: C12H13NO3
• Molecular weight: 219.24 g/mol
• InChIKey: ZXNRTKGTQJPIJK-UHFFFAOYSA-N
• SMILES: COC1=CC=C(C=C1)C(=O)N2CCCC2=O

References

• PMID 22552003
• PMID 19025058