Ampicillin

Category: pharmacological

Pharmacological Mechanism

Aminopenicillin β-lactam — broader spectrum than penicillin (adds Listeria, Enterococcus, some gram-negatives). IV use in meningitis empiric coverage + Listeria-targeted therapy in elderly + immunocompromised. Renal-cleared.

Half-Life (t½)

IV: 1h, PO: 1.45h

Dosing Guidelines

• IV: Typical 1000mg (Range: 250 - 2000 mg)

Target Organ Systems

• renal