Albendazole

Category: pharmacological

Aliases: Albenza

Pharmacological Mechanism

Benzimidazole anthelmintic — binds parasite β-tubulin disrupting microtubule assembly → glucose uptake failure → starvation. Broad spectrum: pinworm, hookworm, whipworm, neurocysticercosis, hydatid disease. Hepatotoxic; bone marrow suppression at high cumulative doses.

Dosing Guidelines

• PO: Typical 400 mg (Range: 200–800 mg)

Target Organ Systems

• digestive
• musculoskeletal
• immune-hematologic

Pathways It Modulates

• Anthelmintic + antiprotozoal targets (inhibitor) — parasite β-tubulin

Chemical Identifiers

• PubChem CID: 2082
• Formula: C12H15N3O2S
• Molecular weight: 265.34 g/mol
• InChIKey: HXHWSAZORRCQMX-UHFFFAOYSA-N
• SMILES: CCCSC1=CC2=C(C=C1)N=C(N2)NC(=O)OC

References

• PMID 10079501