R-Alpha Lipoic Acid

Category: other

Aliases: r-ala, alpha lipoic acid

Pharmacological Mechanism

Mitochondrial cofactor; potent antioxidant; AMPK activation.

Half-Life (t½)

PO: 0.5h

Dosing Guidelines

• PO: Typical 300 (Range: 100–600)

Target Organ Systems

• nervous
• endocrine

Pathways It Modulates

• Reactive oxygen species (ROS) + oxidative stress (activator) — α-lipoic acid (R-enantiomer)

Chemical Identifiers

• PubChem CID: 6112
• Formula: C8H14O2S2
• Molecular weight: 206.32 g/mol
• InChIKey: AGBQKNBQESQNJD-SSDOTTSWSA-N
• SMILES: C1CSS[C@@H]1CCCCC(=O)O

References

• PMID 19664689