Aclidinium

Category: pharmacological

Aliases: Tudorza

Pharmacological Mechanism

Inhaled long-acting muscarinic antagonist (LAMA) — quaternary ammonium for minimal systemic exposure. Twice-daily dosing for COPD maintenance. Rapid plasma hydrolysis vs tiotropium's slow dissociation drives the dosing-frequency difference.

Half-Life (t½)

INH: 2h

Dosing Guidelines

• INH: Typical 0.4mg (Range: 0.4 - 0.4 mg)

Target Organ Systems

• nervous
• respiratory