Osteoclast

Large, multinucleated cells responsible for bone resorption, breaking down bone tissue to release minerals and facilitate bone remodeling.

Key Functions:

• Resorbs bone tissue.
• Releases calcium and phosphate into the blood.
• Involved in bone remodeling and repair.
• Regulated by parathyroid hormone and calcitonin.

Interacting Systems & Components:

• Bone (resorbs)
• Parathyroid Hormone (PTH) (stimulated by)
• Calcitonin (inhibited by)
• Musculoskeletal System (key for bone health)
• Macrophage (related to lineage)