Programmable Cartesian or acoustic laboratory robot dispensing microliter-to-nanoliter reagent and compound volumes across high-density microplates.
Specifications & Metrics
measures
Volumetric precision (CV%), serial concentration dilutions, and plate-to-plate compound stamping throughput
Core Principles & Analysis
Automated liquid handlers replace manual pipetting with motorized 96-, 384-, or 1536-channel air-displacement or positive-displacement pipetting heads mounted on a multi-axis Cartesian deck integrated with plate grippers, shakers, and incubators.
Acoustic droplet ejection (ADE) liquid handlers use focused ultrasound pulses to launch 2.5-nanoliter droplets directly from a source microplate well into an inverted destination plate without physical pipette tips, eliminating cross-contamination and plastic waste.
In high-throughput pharmacology, liquid-handling workstations execute automated 10-point serial dilutions for IC50/EC50 curves, cherry-pick primary screening hits, and miniaturize biochemical and cell-based assays into 1536-well formats.