Sphingosine
Forms the backbone of sphingolipids, consisting of an 18-carbon unsaturated amino alcohol, acting as a crucial precursor for ceramide and other signaling molecules.
Key Functions:
- Precursor for ceramide and other complex sphingolipids.
- Phosphorylated to sphingosine-1-phosphate, a potent signaling molecule.
- Involved in cell growth, differentiation, and apoptosis.
Interacting Systems & Components:
- Ceramide (precursor for)
- Sphingomyelin (component of)
- Glycosphingolipids (component of)
- Sphingosine Kinase (phosphorylates sphingosine)
- Cell Signaling Pathways (key modulator)