Low-Density Lipoprotein

Transports cholesterol from the liver to peripheral cells, where it is internalized via receptor-mediated endocytosis, often referred to as 'bad cholesterol' due to its association with atherosclerosis.

Key Functions:

• Delivers cholesterol to cells for membrane synthesis and steroid hormone production.
• Excess levels contribute to plaque formation in arteries.

Interacting Systems & Components:

• Cholesterol (primary cargo)
• Intermediate Density Lipoprotein (derived from)
• LDL Receptor (mediates cellular uptake)
• Arteries (accumulation leads to atherosclerosis)
• Cells (delivers cholesterol to)