Category: pharmacological
Aliases: Atromid-S, ethyl 2-(4-chlorophenoxy)-2-methylpropanoate
First-generation fibrate (PPAR-α agonist) that activates lipoprotein lipase and lowers serum triglycerides + LDL. Largely supplanted by gemfibrozil and fenofibrate due to a 1978 WHO trial showing increased non-cardiovascular mortality. Highly protein-bound (~96-97%) — clinically relevant as a warfarin plasma-binding displacer.